Automatic Cell Manipulation and Patterning System by using Dielectrophoresis (DEP):
My research in Ph.D. is on cell manipulation and patterning with a robotic-aided automatic system. Equipped with a microchip that can generate electric fields, the system enables micro particle (including biological cell) translation and patterning via the DEP force.
High-quality single-bead patterns are constructed through the system. Multiple relays are connected to the microchip to energize individual dot-electrodes to generate different electric field forms for micro bead holding and patterning. PS bead pattern with orange fluorescent color is fabricated. 
Biological cell cluster patterning is conducted through the system. Different cell cluster patterns are formed on the substrate by controlling the opening of each dot electrode on the microchip. 
A large-scale yeast cell pattern is achieved using the moving platform of the microscope. The relative movement between the microchip and the substrate on the platform aids in constructing cell cluster patterns anywhere in the substrate. 
Equipped with a large-scale quadrupole microchip, the system enables mouse embryo alignment and rotation for laser drilling. 